Dual-energy / energy subtraction
Two near-simultaneous radiographs are acquired at low and high tube kV. At low kV the photoelectric effect dominates (proportional to Z cubed over E cubed) giving strong bone versus soft-tissue contrast; at high kV Compton scatter dominates, giving low bone contrast. A weighted, pixel-by-pixel subtraction produces two images: low kV minus high kV cancels soft tissue to give a bone-only image, while high kV minus low kV cancels bone to give a soft-tissue-only, bone-suppressed image revealing a lung nodule. Only two images are used and no pre-contrast mask is needed, unlike temporal digital subtraction angiography.
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