Infographics / Nuclear Medicine

NaI(Tl) crystal: thickness vs resolution/sensitivity

Cross-section of a gamma camera head. A 140 keV photon is absorbed by the photoelectric effect in a single monolithic sodium iodide (thallium) crystal, producing a burst of about 5000 scintillation light photons that spread through a flat transparent light guide onto several photomultiplier tubes. The crystal is hygroscopic and brittle, so it is hermetically sealed in an aluminium housing. A trade-off panel shows that a thinner crystal gives better intrinsic spatial resolution (narrow light spread) while a thicker crystal gives higher detection efficiency but wider light spread and more depth-of-interaction blur.

Gamma camera NaI(Tl) crystal: scintillation and the thickness trade-off Cross-section of a gamma camera head. A 140 keV photon is absorbed by the photoelectric effect in a single monolithic sodium iodide (thallium) crystal, producing a burst of about 5000 scintillation light photons that spread through a flat transparent light guide onto several photomultiplier tubes. The crystal is hygroscopic and brittle, so it is hermetically sealed in an aluminium housing. A trade-off panel shows that a thinner crystal gives better intrinsic spatial resolution (narrow light spread) while a thicker crystal gives higher detection efficiency but wider light spread and more depth-of-interaction blur. Gamma camera crystal — cross-section (NaI(Tl)) photomultiplier tubes (PMTs) flat transparent light guide NaI(Tl) crystal scintillation light photons 140 keV γ photon (99mTc) absorbed by photoelectric effect hermetically sealed aluminium housing — crystal is hygroscopic & brittle (not waterproof) Crystal thickness trade-off thinner crystal → better intrinsic spatial resolution (narrow light spread, little DOI blur) thicker crystal → higher detection efficiency (favoured for higher-energy photons; wider spread) Light output ∝ absorbed energy: a 140 keV photon → ~5000 scintillation photons (NaI(Tl) ≈ 3–4 × 10⁴ photons per MeV), shared across the PMTs to locate the event.

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