Infographics / MRI Physics

Spin-echo vs gradient-echo pulse sequences

Two pulse-sequence lanes drawn on a shared time axis with excitation aligned at time zero. Top lane, spin echo: a 90 degree excitation, then a 180 degree refocusing pulse at TE over 2, then an echo at TE; the repetition time TR is long and spans the whole width. A note states the 180 degree pulse rephases spins and cancels static B0 inhomogeneity giving true T2. Bottom lane, gradient echo: a smaller flip-angle alpha excitation, an echo formed by reversal of the readout gradient with no 180 degree pulse, marked at a much shorter TE, and a short TR so several excitations repeat across the same width. A note states this is faster with shorter TR but the signal decays with T2 star and is sensitive to susceptibility, not true T2.

Spin echo versus gradient echo pulse-sequence timing Two pulse-sequence lanes drawn on a shared time axis with excitation aligned at time zero. Top lane, spin echo: a 90 degree excitation, then a 180 degree refocusing pulse at TE over 2, then an echo at TE; the repetition time TR is long and spans the whole width. A note states the 180 degree pulse rephases spins and cancels static B0 inhomogeneity giving true T2. Bottom lane, gradient echo: a smaller flip-angle alpha excitation, an echo formed by reversal of the readout gradient with no 180 degree pulse, marked at a much shorter TE, and a short TR so several excitations repeat across the same width. A note states this is faster with shorter TR but the signal decays with T2 star and is sensitive to susceptibility, not true T2. Spin echo TR (long, hundreds–thousands ms) 90° 180° (at TE/2) echo TE 180° pulse rephases spins → cancels static B0 inhomogeneity → true T2 contrast. Gradient echo TR (short, ~5–50 ms) α (<90°) echo TE (short) readout gradient reversal (no 180°) Smaller flip angle, echo formed by gradient reversal → faster imaging, shorter TR. Trade-off: no refocusing pulse → decays with T2*, susceptibility-sensitive (not true T2). time

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